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Updated: Mar 6, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Part I. The role of Staphylococcus aureus in the pathophysiology of dermatologic disease
Selcen Sila Yuksel1, Richard L Gallo1, Tissa R Hata1
1University of California San Diego Department of Dermatology, 9500 Gilman Drive, La Jolla, CA 92093-0869.
Abstract:
In this first part of a two-part continuing medical education series, we examine the impact of Staphylococcus aureus (S. aureus) resistance and its pathogenic mechanisms, such as toxins, virulence factors, superantigens, quorum sensing, and biofilm formation. Next, we explore how S. aureus infection contributes to delayed wound healing, impetigo, and staphylococcal scalded skin syndrome. Additionally, S. aureus plays a crucial role in the pathophysiology of dermatologic diseases that goes beyond infection, including atopic dermatitis, cutaneous T-cell lymphoma, epidermolysis bullosa, and others. Understanding S. aureus will help dermatologists better understand and more effectively treat various skin conditions.
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