Updates and evolving care paradigms for pre-menopausal patients with endometrial cancer

The rates of endometrial cancer are increasing for pre-menopausal patients with first pregnancy attempt now surpassing 30 years. This combination has created unique challenges for pre-menopausal patients with endometrial cancer, and deciding the best treatment options can be complicated for clinicians and patients. This narrative review will discuss current, broadly accepted patient selection criteria and treatment and surveillance strategies for young patients who wish to retain their fertility. Efforts to expand selection criteria for non-surgical management, including novel treatment options for select tumors, and perspectives on nuanced clinical scenarios will also be discussed.