Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

711
Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
711
Endotracheal Intubation II: Nursing Management01:17

Endotracheal Intubation II: Nursing Management

3.1K
Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
3.1K
Endotracheal Tube Extubation01:24

Endotracheal Tube Extubation

5.1K
Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
5.1K
Endotracheal Intubation I: Procedure01:15

Endotracheal Intubation I: Procedure

10.2K
Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
10.2K
Trachea01:22

Trachea

5.6K
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
5.6K
Larynx01:21

Larynx

5.5K
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative Analysis of Endoscopic and Microscopic Myringoplasty.

International archives of otorhinolaryngology·2025
Same author

Olfactory Training and Oral Corticosteroid Therapy for Persistent Postinfectious Hyposmia.

International archives of otorhinolaryngology·2025
Same author

Dysphagia in patients with coronavirus disease undergoing orotracheal intubation.

Laryngoscope investigative otolaryngology·2022
Same author

Incidence of Laryngotracheal Lesions After Orotracheal Intubation in Coronavirus Disease Patients.

The Laryngoscope·2021
Same author

The Importance of Inspiratory Maneuver for Benign Laryngeal Lesions.

International archives of otorhinolaryngology·2020
Same author

Clinical and functional correlations of the difference between slow vital capacity and FVC.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia·2019

Related Experiment Video

Updated: Mar 6, 2026

The Rigid Tube as an Alternative in Controlling the Problematic Airway
08:26

The Rigid Tube as an Alternative in Controlling the Problematic Airway

Published on: June 6, 2020

6.9K

Larynx Injuries After Orotracheal Intubation: What are Risk Factors Observed in Patients with Covid?

Leticia Felix1, Gabriel de Souza Mares1, Lara Freire Bezerril Soares1

  • 1Department of Otolaryngology, Hospital do Servidor Público Estadual de São Paulo (HSPE), São Paulo, SP, Brazil.

International Archives of Otorhinolaryngology
|March 5, 2026
PubMed
Summary

COVID-19 patients undergoing orotracheal intubation face higher risks of laryngotracheal injury. Factors like elevated leukocytes, lymphopenia, and larger endotracheal tubes increase this risk, impacting patient outcomes.

Keywords:
COVID-19SARS-CoV-2laryngostenosislarynx

More Related Videos

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
04:46

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation

Published on: January 17, 2011

22.2K
Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes
03:58

Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes

Published on: August 2, 2024

2.3K

Related Experiment Videos

Last Updated: Mar 6, 2026

The Rigid Tube as an Alternative in Controlling the Problematic Airway
08:26

The Rigid Tube as an Alternative in Controlling the Problematic Airway

Published on: June 6, 2020

6.9K
A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
04:46

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation

Published on: January 17, 2011

22.2K
Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes
03:58

Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes

Published on: August 2, 2024

2.3K

Area of Science:

  • Critical Care Medicine
  • Otolaryngology
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19) has necessitated advanced respiratory support, including orotracheal intubation (OTI).
  • Laryngotracheal injuries are a potential complication of OTI, particularly in critically ill patients.
  • Understanding risk factors for these injuries in COVID-19 patients is crucial for improving care.

Purpose of the Study:

  • To identify and evaluate risk factors associated with laryngotracheal injuries in COVID-19 patients who underwent OTI.
  • To inform clinical practice and reduce the incidence of post-intubation airway complications.

Main Methods:

  • A cohort study included COVID-19 patients requiring OTI between March and October 2020.
  • Data collected included patient demographics, clinical parameters at admission and intubation, and intubation details.
  • Outpatient videoendoscopy was used to assess laryngotracheal injury in a subset of discharged patients.

Main Results:

  • Out of 421 intubated COVID-19 patients, 172 (40.9%) were discharged and 249 (59.1%) died.
  • Increased leukocyte count, lymphopenia, hypoalbuminemia, elevated arterial lactate, troponin, and total bilirubin were associated with higher injury risk.
  • Use of larger caliber endotracheal tubes and pronation therapy also correlated with increased risk.

Conclusions:

  • Specific laboratory markers at admission (leukocytosis, lymphopenia, hypoalbuminemia, elevated lactate, troponin, bilirubin) are predictive of laryngotracheal injury.
  • Mechanical factors during intubation (larger ETT caliber) and treatment (pronation) are also significant risk factors.
  • Patients exhibiting heightened inflammatory responses or coagulation disorders during OTI are at greater risk for airway injury.