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Updated: Mar 6, 2026

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
Published on: August 16, 2024
Functional outcome after vertical parasagittal hemispherotomy in pediatric hemimegalencephaly: Insights from a single
Van Dinh Tran1, Nhung Hong Ta2, Minh Chau Thu Nguyen3
1Department of Neurosurgery 1, Viet Duc University Hospital, Ha Noi, Vietnam.
Insights
Parasagittal vertical hemispherotomy (PSVH) offers effective seizure control for children with drug-resistant epilepsy from unilateral brain abnormalities. This surgical approach demonstrates safety and positive outcomes, supporting early intervention.
Area of Science:
- Neurosurgery
- Pediatric Neurology
- Epileptology
Background:
- Drug-resistant epilepsy (DRE) in children often stems from unilateral hemispheric abnormalities.
- Parasagittal vertical hemispherotomy (PSVH) is an emerging surgical technique for these conditions.
- PSVH is gaining traction globally for its potential to improve seizure control.
Background:
Parasagittal vertical hemispherotomy (PSVH) is a surgical technique increasingly adopted in epilepsy centers worldwide, providing excellent seizure control in children with drug-resistant epilepsy (DRE) due to unilateral hemispheric abnormalities.
Case Description:
We report a case of a 5-year-old girl with DRE secondary to hemimegalencephaly and treated with PSVH. At 11 months postoperatively, the patient achieved complete seizure freedom without major complications. This successful case supports the effectiveness and safety of PSVH in managing DRE caused by unilateral hemispheric lesions and highlights the importance of early surgical intervention in this pediatric population.
Conclusion:
PSVH achieves reliable seizure control with reduced surgical morbidity and favorable functional outcomes in children with hemispheric epileptogenic disorders.

