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Contrast-specific conversion factor for accurate radiation dose estimation in contrast-enhanced abdominal computed
Yoshinori Funama1, Daisuke Sakabe2, Takeshi Nakaura3
1Department of Medical Image Analysis, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Journal of Clinical Imaging Science
|March 5, 2026
Summary
This study introduces a contrast-specific conversion factor (cCF) to improve radiation dose estimation in contrast-enhanced CT (CECT) scans. Calculating cCF using organ dose ratios between CECT and non-enhanced CT (NECT) enhances accuracy.
Area of Science:
- Medical Imaging
- Radiology
- Radiation Dosimetry
Background:
- Accurate radiation dose estimation in computed tomography (CT) is crucial, especially for contrast-enhanced examinations.
- Non-enhanced CT (NECT) and contrast-enhanced CT (CECT) involve different radiation doses.
- Improving dose assessment for CECT is essential for patient safety and diagnostic accuracy.
Purpose of the Study:
- To determine a contrast-specific conversion factor (cCF) for abdominal CT.
- To establish a method for more accurate radiation dose estimation in CECT.
- To quantify the dose differences between NECT and CECT using organ dose ratios.
Main Methods:
- The study involved 33 adult patients undergoing both NECT and CECT.
- Monte Carlo simulations were used to estimate organ doses (liver, spleen, kidneys) for NECT and CECT.
- The contrast-specific conversion factor (cCF) was calculated as the ratio of CECT organ dose to NECT organ dose.
Main Results:
- Mean organ doses increased from NECT to CECT: liver (10.45 to 15.83 mGy), spleen (11.19 to 17.56 mGy), and kidneys (11.47 to 20.75 mGy).
- The calculated mean cCF values were 1.52 for the liver, 1.83 for the spleen, and 1.87 for the kidneys.
- cCF values demonstrated dependency on scan protocol, CT vendor, and X-ray photon energy.
Conclusions:
- The contrast-specific conversion factor (cCF) provides a more accurate method for radiation dose assessment in CECT.
- Applying cCF to NECT-based dose estimates improves the evaluation of radiation exposure during contrast-enhanced CT examinations.
- This approach aids in optimizing radiation safety protocols in abdominal CT imaging.
Keywords:
Contrast-enhanced computed tomographyContrast-specific conversion factorNon-enhanced computed tomographyRadiation dose estimationMore Related Videos
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