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Published on: May 19, 2020
Posterior Mitral Valve Acute Infective Endocarditis Complicated With Brain Abscess and Infection-Related
Mikunthan Mithuriha1, Raja Hettiarachchi1, Thamotharam Balachandran2
1Internal Medicine, Colombo North Teaching Hospital, Ragama, LKA.
Abstract:
We report the case of a 48-year-old previously unevaluated woman who presented with a short febrile illness with multi-organ involvement and was later diagnosed with acute methicillin-sensitive Staphylococcus aureus infective endocarditis of the posterior mitral valve. Her illness was complicated by septic embolization, leading to cerebral abscesses and infection-related glomerulonephritis, causing acute kidney injury. She had multiple septic teeth, which were thought to be the source of bacteremia. She was managed with multidisciplinary input involving cardiology, neurology, neurosurgery, microbiology, and oral maxillofacial surgery. Six weeks of intravenous antibiotics and removal of dental foci resulted in complete clinical and biochemical recovery. Follow-up transesophageal echocardiogram demonstrated resolution of the vegetation, and interval imaging showed a reduction in the size of the brain abscess. This case highlights the importance of early recognition of infective endocarditis and the need for multidisciplinary care in the presence of systemic complications.
Insights
A woman with Staphylococcus aureus infective endocarditis experienced multi-organ complications, including brain abscesses and acute kidney injury. Prompt multidisciplinary treatment with antibiotics and dental intervention led to full recovery.
Area of Science:
- Cardiology
- Infectious Diseases
- Nephrology
- Neurology
Background:
- Infective endocarditis is a serious infection of the heart valves.
- Staphylococcus aureus is a common cause of infective endocarditis.
- Systemic complications can arise from septic embolization.
Related Concept Videos
Mitral Stenosis I: Introduction
Endocarditis I: Introduction
Mitral Regurgitation I: Introduction
Mitral Stenosis III: Medical Management
Endocarditis III: Medical Management
Endocarditis II: Clinical Features of Infective Endocarditis

