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Relapsing, steroid-refractory ICANS after CAR T-cell therapy: diagnostic work-up and response to delayed repeated

Rosemarijn M Van Nijendaal1, Joost S P Vermaat2, Victor J Geraedts3

  • 1Department of neurology, Leiden University Medical Center, Leiden, the Netherlands. r.m.van_nijendaal@lumc.nl.

Haematologica
|March 5, 2026
PubMed
Abstract

No abstract available in PubMed .

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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.