Prevalence of Malnutrition in Children with Cleft Conditions in Madagascar: A Cross-Sectional Study
Daniel D Otobo1, Charlotte Steppling1, Ashley Myles1
1Global Surgery Research Department, Operation Smile, Virginia Beach, VA, USA.
Insights
Pediatric malnutrition is extremely high in children with clefts in Madagascar, with 96% affected. This significantly impacts surgical readiness and highlights a critical public health issue requiring urgent nutritional intervention.
Area of Science:
- Pediatric Surgery
- Nutritional Science
- Public Health
Background:
- Cleft lip and palate conditions can significantly impact a child's nutritional status.
- Malnutrition poses a major challenge for surgical candidacy and postoperative recovery in pediatric patients.
- Understanding malnutrition prevalence is crucial for optimizing care pathways in resource-limited settings.
Purpose of the Study:
- To determine the prevalence, patterns, and distribution of malnutrition in pediatric patients undergoing evaluation for cleft surgery in Madagascar.
- To assess the nutritional status of children with cleft lip and/or palate (CL/P) in relation to surgical readiness.
Main Methods:
- A retrospective cross-sectional study of 658 pediatric patients evaluated for cleft surgery between 2020 and 2023.
- Anthropometric measurements including weight-for-length/height Z-scores and mid-upper arm circumference were analyzed.
- Patients were categorized by gender, age, and malnutrition severity based on World Health Organization (WHO) growth charts.
Main Results:
- A staggering 96% of pediatric patients with clefts presented with malnutrition (mild to severe).
- 83% required enrollment in nutritional programs for optimization before surgical consideration.
- Infants under 6 months exhibited the highest prevalence (52.4%) and severity (68.1%) of malnutrition.
Conclusions:
- Malnutrition is highly prevalent (96%) among pediatric patients with clefts in Madagascar, significantly higher than the general under-5 population (47%).
- The findings underscore the critical need for integrated nutritional support within cleft care programs.
- Early nutritional intervention is essential for improving surgical outcomes in this vulnerable population.
Abstract:
ObjectiveThis study aims to assess the prevalence, patterns, and distribution of malnutrition among pediatric patients evaluated for cleft surgery in Madagascar.MethodologyDesign/Setting: This Retrospective cross-sectional study assessed 658 patients who presented for cleft care between 2020 and 2023 during surgical programs of an International Cleft Surgical Non-Profit Organization in Madagascar.Intervention/Outcome MeasuredPatient demographics and anthropometry of all patients were measured. The weight-for-length Z score/weight-for-height Z score World Health Organization Growth Chart Z scores, as well as mid-upper arm circumference for patients aged > 6 months to 59 months, were measured and recorded. Patients were grouped based on gender and age.ResultsOf the 658 patients screened for surgery, 96% were malnourished (mild to severe malnutrition), and 83% of the screened patients had to be enrolled in the nutrition program (Z scores ≤ -2standard deviation) for nutritional optimization before surgery could be considered. At the time of this study, 239 patients had received surgery, while 309 were awaiting surgery. The majority had combined cleft lip and palate (59%), and over half of the mothers were unable to breastfeed their children at all due to the cleft condition(s) (53%). The highest prevalence (52.4%) and severity (68.1%) of malnutrition was observed among infants under 6 months old.ConclusionThe malnutrition status among patients with a cleft lip and/or palate in Madagascar is high (96%, p < .001). When children with cleft conditions who were malnourished (96%) were compared with the under-5 malnutrition status among non-cleft patients (47%) in Madagascar, it was a ratio of 2:1.
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