Prevalence of Malnutrition in Children with Cleft Conditions in Madagascar: A Cross-Sectional Study

Daniel D Otobo1, Charlotte Steppling1, Ashley Myles1

  • 1Global Surgery Research Department, Operation Smile, Virginia Beach, VA, USA.

Insights

Pediatric malnutrition is extremely high in children with clefts in Madagascar, with 96% affected. This significantly impacts surgical readiness and highlights a critical public health issue requiring urgent nutritional intervention.

Area of Science:

  • Pediatric Surgery
  • Nutritional Science
  • Public Health

Background:

  • Cleft lip and palate conditions can significantly impact a child's nutritional status.
  • Malnutrition poses a major challenge for surgical candidacy and postoperative recovery in pediatric patients.
  • Understanding malnutrition prevalence is crucial for optimizing care pathways in resource-limited settings.

Purpose of the Study:

  • To determine the prevalence, patterns, and distribution of malnutrition in pediatric patients undergoing evaluation for cleft surgery in Madagascar.
  • To assess the nutritional status of children with cleft lip and/or palate (CL/P) in relation to surgical readiness.

Main Methods:

  • A retrospective cross-sectional study of 658 pediatric patients evaluated for cleft surgery between 2020 and 2023.
  • Anthropometric measurements including weight-for-length/height Z-scores and mid-upper arm circumference were analyzed.
  • Patients were categorized by gender, age, and malnutrition severity based on World Health Organization (WHO) growth charts.

Main Results:

  • A staggering 96% of pediatric patients with clefts presented with malnutrition (mild to severe).
  • 83% required enrollment in nutritional programs for optimization before surgical consideration.
  • Infants under 6 months exhibited the highest prevalence (52.4%) and severity (68.1%) of malnutrition.

Conclusions:

  • Malnutrition is highly prevalent (96%) among pediatric patients with clefts in Madagascar, significantly higher than the general under-5 population (47%).
  • The findings underscore the critical need for integrated nutritional support within cleft care programs.
  • Early nutritional intervention is essential for improving surgical outcomes in this vulnerable population.

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