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Balancing Cure and Quality of Life: Navigating Functional Outcomes in Localized Prostate Cancer.

Abby L Grier1, Erik Briers2, Randie E White3

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Managing localized prostate cancer involves balancing treatment effectiveness with quality of life. This review highlights optimizing surgical and radiation therapy (RT) outcomes while addressing sexual, urinary, and psychosocial health for better survivorship.

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Area of Science:

  • Oncology
  • Urology
  • Psychosocial Health

Background:

  • Localized prostate cancer presents diverse management options, from active surveillance to surgery and radiation therapy (RT).
  • Treatment choices are influenced by tumor specifics, patient health, and personal objectives.
  • While survival and functional outcomes have improved with advanced techniques, quality of life impacts persist.

Purpose of the Study:

  • To examine the relationship between localized prostate cancer treatment choices, functional results, and psychosocial factors.
  • To identify key areas for enhancing patient care and survivorship.
  • To underscore the importance of aligning treatment decisions with patient values.

Main Methods:

  • This review synthesizes current literature on localized prostate cancer management.
  • It explores advancements in surgical and radiation techniques.
  • It discusses the impact of treatment on sexual, urinary, bowel function, and psychological well-being.

Main Results:

  • Optimized surgical strategies and precise RT can improve functional outcomes and reduce toxicity.
  • Sexual, urinary, and bowel dysfunctions are common side effects requiring management.
  • Psychological distress, including anxiety and depression, is prevalent in survivors.

Conclusions:

  • Multidisciplinary care integrating functional and psychosocial support is crucial for improving quality of life.
  • Aligning treatment decisions with patient priorities minimizes decisional regret.
  • Personalized care plans are essential for navigating localized prostate cancer survivorship.