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Mechanistic Insights from Human Studies in Axial Spondyloarthritis: A T Cell Story

Joy Um1, Michael A Paley2

  • 1Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Current Rheumatology Reports
|March 5, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Ankylosing spondylitisAxial spondyloarthritisHLA-B*27IL-17T cell receptor

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Keywords:
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