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Green Stool Predominance in Babies and Subsequent Bowel Function at 1-2 Years of Age
L Typpö1, T Solasaari1,2, K Korpela3
1Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Insights
Early infant green stools or frequent crying were linked to mild gastrointestinal issues later in infancy. These findings in healthy term babies suggest potential links to gut microbiota changes.
Area of Science:
- Pediatric gastroenterology
- Infant health
- Microbiome research
Background:
- Early life bowel function in term infants can vary.
- Green stools and excessive crying are common infant occurrences.
- Long-term implications of these early variations require investigation.
Purpose of the Study:
- To investigate the association between early-life bowel characteristics (green stools, crying) and later bowel function in term infants.
- To determine if these early signs predict benign gastrointestinal symptoms at 1-2 years of age.
Main Methods:
- Prospective cohort study (HELMİ cohort) of term infants.
- Comparison of infants with predominantly green stools and high crying frequency against matched controls.
- Bowel function assessment at 1-2 years of age.
Main Results:
- Infants with early green stools showed increased reports of abdominal symptoms (1.5-2x) and stool-mucus at 1-2 years.
- Infants who cried most frequently exhibited higher defecation frequency and more frequent stool-mucus at 1 year.
- No severe gastrointestinal dysfunction was observed in any group.
Conclusions:
- Occasional abdominal pain and green stools in healthy term infants are associated with benign gastrointestinal symptoms later in infancy.
- These functional variations may indicate altered gut microbiota.
- Further research is warranted to explore the role of microbiota in these infant bowel function variations.
Aim:
To study the relationship between bowel function after birth and at 1-2 years of age in the prospective HELMi cohort of term infants.
Methods:
We focused on infants with predominantly green stools (n = 152) for three consecutive weeks in early life and their sex, age, and delivery mode-matched controls (n = 300), and evaluated bowel function at 1-2 years. We also evaluated bowel function in babies who had cried the most (n = 179) and compared the findings with the rest of the cohort (n = 689).
Results:
There were no alarming signs of gastrointestinal dysfunction in any of the infants. Infants with green stools in early life had 1.5-2 times more reports of abdominal symptoms at 1-2 years compared to controls (p < 0.005), and stool-mucus was twice as frequent at 1 year (p < 0.05). Compared to controls, 1-year-old infants who cried most as babies had a higher frequency of defecation (a median of 14 per week [IQR 8-17] vs. 12 [IQR 7-15]; p < 0.05) and showed twice as frequent stool-mucus at 1 year (p < 0.05).
Conclusion:
In healthy term babies, occasional abdominal pain or predominantly green stools were associated with benign gastrointestinal symptoms in later infancy. This functional variation may reflect altered microbiota, warranting further research.
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