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Isolation of Small Noncoding RNAs from Human Serum
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Serum miR-199a-3p and miR-103a-3p are possible biomarkers for the onset of multiple sclerosis

Simone Agostini1, Roberta Mancuso2, Maria Barbara Pasanisi1

  • 1IRCCS Fondazione Don Carlo Gnocchi, Piazzale Carlo GIrola 30, 20162, Milan, Italy.

Scientific Reports
|March 5, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
BiomarkersEpigeneticsMultiple sclerosisRehabilitationSerummiRNAs

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Multiple Sclerosis l: Introduction01:19

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Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

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