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Related Concept Videos

Complement System01:27

Complement System

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The complement system is a group of approximately 20 plasma proteins that strengthen the body's defenses against infections through opsonization, inflammation, and cell lysis. Opsonization involves coating pathogens with complement proteins, making them more recognizable and facilitating phagocyte engulfment. Certain complement proteins induce inflammation that attracts immune cells to the site of infection. Cell lysis involves the destruction of pathogens through the formation of a...
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Inflammatory Response01:28

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An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
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Related Experiment Video

Updated: Mar 7, 2026

Digestion of Whole Mouse Eyes for Multi-Parameter Flow Cytometric Analysis of Mononuclear Phagocytes
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Digestion of Whole Mouse Eyes for Multi-Parameter Flow Cytometric Analysis of Mononuclear Phagocytes

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Systemic inflammation triggers local complement production in the mouse retina and RPE

Vittoria Spero1,2, Pascal Escher3,4, Sophie Braga-Lagache5

  • 1Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse, Bern, 3010, Switzerland. vittoria.spero@insel.ch.

Journal of Neuroinflammation
|March 5, 2026
PubMed
Summary

No abstract available in PubMed .

Keywords:
C3ComplementEyeImmune systemInflammationRetinaRetinal pigment epithelium

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