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Allergic Reactions: Anaphylaxis

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...

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Related Experiment Video

Updated: Mar 7, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

How Good Is the Australian Paediatric Baseline Series at Detecting Allergic Contact Dermatitis?

James Fuller¹, Amanda Palmer¹, Claire Grills²

¹Occupational Dermatology Research and Education Centre, Skin Health Institute, Melbourne, Victoria, Australia.

Contact Dermatitis

|March 6, 2026

Summary

No abstract available in PubMed .

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