Related Experiment Video
Updated: Mar 7, 2026
Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Dysphagia Rehabilitation Outcomes in Head and Neck Cancer Patients With Radiation Associated Dysphagia: Does Time
Hanne Massonet1,2,3, Ann Goeleven1,3, Sandra Nuyts4,5
1KU Leuven, Department of Neurosciences, Research Group Experimental Oto-rhino-laryngology, Leuven, Belgium.
Background:
Since radiation-associated dysphagia may evolve in the months to years following (chemo)radiotherapy (C/RT), it is important to determine whether swallowing-related outcomes vary according to the time elapsed since cancer treatment. This may help to determine the time window in which a patient might benefit most from dysphagia rehabilitation.
Methods:
Fifty-four patients were stratified into three groups based on the time since completion of the C/RT: < 1 year; 1-5 years; > 5 years post-C/RT. Differences in swallowing-related outcomes were compared at baseline and after 8 weeks of swallowing rehabilitation.
Results:
Swallowing-related outcomes were significantly worse at baseline in patients who were more than 5 years post-C/RT compared to those less than 5 years post-C/RT. Nevertheless, these patients still show significant and comparable improvements in swallowing-related outcomes after 8 weeks of swallowing rehabilitation.
Conclusions:
Although patients more than 5 years post-C/RT exhibited worse swallowing-related outcomes compared to those less than 5 years post-C/RT, these patients remain viable candidates for swallowing rehabilitation.
Trial Registration:
ClinicalTrials.gov identifier: ISRCTN57028065.
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