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Unveiling an Uncommon Complication: Pleural Effusion Secondary to Pioglitazone Use
Ranjana Chimauriya1, Abhinandan Chittal2, Khalid Malik2
1MedStar Health Georgetown University (Baltimore) Internal Medicine Residency Program, USA.
Pioglitazone, a diabetes drug, can rarely cause fluid buildup in the lungs (pleural effusion) without heart failure. Stopping the medication resolved the effusion in this case.
Area of Science:
- Endocrinology
- Pulmonology
- Pharmacology
Background:
- Pioglitazone is a PPAR-γ agonist used for Type 2 diabetes.
- Known side effects include edema and fluid retention.
- Isolated pleural effusion is a rare adverse effect.
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