Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

786
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
786
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

718
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
718
Mitral Regurgitation IV: Nursing Management01:28

Mitral Regurgitation IV: Nursing Management

445
Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
445
Mitral Regurgitation II: Clinical Features and Diagnostic Tests01:23

Mitral Regurgitation II: Clinical Features and Diagnostic Tests

666
Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
666
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

1.0K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.0K
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

968
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
968

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Angiotensin Receptor Neprilysin Inhibitor in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Regurgitation: The PRAISE-MR Randomized Trial.

Circulation·2026
Same author

Severe aortic regurgitation with acute decompensation as initial presentation of Behçet's syndrome: a case report.

European heart journal. Case reports·2025
Same author

Role of contrast-enhanced echocardiography in the management of periaortic pseudoaneurysm: mind the gap.

European heart journal·2025
Same author

Low-gradient normal-flow aortic stenosis: don't forget the assessment of the flow rate.

Acta cardiologica·2025
Same author

Mixed valvular heart disease: diagnosis and management.

European heart journal·2025
Same author

The reversibility of cardiac damage after transcatheter aortic valve implantation and short-term outcomes in a real-world setting.

European heart journal. Cardiovascular Imaging·2025

Related Experiment Video

Updated: Mar 7, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

1.1K

Right Ventricular Function in Patients With Significant Tricuspid Regurgitation.

Xavier Galloo1, Philippe Unger1,2

  • 1Department of Cardiology - Valve Clinic, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), B-1090 Brussels, Belgium.

Reviews in Cardiovascular Medicine
|March 6, 2026
PubMed
Summary

Assessing right ventricular (RV) systolic function is crucial for managing significant tricuspid regurgitation (TR). Early detection of RV dysfunction predicts outcomes and guides timely interventions for improved survival.

Keywords:
reviewright ventricular functionrisk assessmenttricuspid valvetricuspid valve insufficiencyventricular remodeling

More Related Videos

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
07:11

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography

Published on: October 28, 2020

3.5K
Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
10:33

Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography

Published on: February 3, 2014

28.7K

Related Experiment Videos

Last Updated: Mar 7, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

1.1K
Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
07:11

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography

Published on: October 28, 2020

3.5K
Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
10:33

Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography

Published on: February 3, 2014

28.7K

Area of Science:

  • Cardiology
  • Cardiac Imaging
  • Echocardiography

Background:

  • Significant tricuspid regurgitation (TR) is a key factor in patient morbidity and mortality.
  • Right ventricular (RV) systolic function is critical for managing TR, influencing symptoms, treatment response, and outcomes.
  • The RV's sensitivity to hemodynamic changes necessitates accurate functional assessment for risk stratification and intervention planning.

Purpose of the Study:

  • To review the pathophysiology, quantitative thresholds, and prognostic significance of RV function assessment in patients with significant TR.
  • To emphasize the importance of RV function evaluation in contemporary TR management.

Main Methods:

  • Echocardiography, including TAPSE, RVFAC, S', speckle-tracking, and 3D imaging, is the primary tool for RV function assessment.
  • Cardiac magnetic resonance (CMR) imaging serves as the reference standard for precise RV volumetric and functional parameter evaluation.
  • Review of existing literature on RV function assessment in TR.

Main Results:

  • Impaired RV systolic function consistently predicts adverse outcomes in severe TR, including heart failure progression, reduced exercise tolerance, and decreased survival.
  • Interventions performed before advanced RV impairment offer symptomatic and survival benefits.
  • Accurate quantification of RV dysfunction is vital for optimizing therapeutic timing and type.

Conclusions:

  • Early recognition and quantification of RV dysfunction are crucial for timely therapy in significant TR.
  • RV function assessment plays a pivotal role in the contemporary management of TR.
  • Optimizing RV function assessment aids in improving patient outcomes and survival.