Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

419
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
419
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

906
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
906
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

528
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
528
Kidney Structure01:45

Kidney Structure

76.0K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
76.0K
Renal Corpuscle01:20

Renal Corpuscle

8.1K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
8.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Objective evaluation of clinical outcomes of laparoscopy-assisted pylorus-preserving gastrectomy for middle-third early gastric cancer.

BMC cancer·2019
Same author

miR‑767‑5p inhibits glioma proliferation and metastasis by targeting SUZ12.

Oncology reports·2019
Same author

Predicting Essential Proteins by Integrating Network Topology, Subcellular Localization Information, Gene Expression Profile and GO Annotation Data.

IEEE/ACM transactions on computational biology and bioinformatics·2019
Same author

Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of the Volatile Oil of Cichorium Glandulosum Boiss et Huet and its Effects on Carbon Tetrachloride-Induced Liver Fibrosis in Rats.

Medical science monitor : international medical journal of experimental and clinical research·2019
Same author

Experimental study on healthy volunteers based on magnetic induction brain edema monitoring system.

Technology and health care : official journal of the European Society for Engineering and Medicine·2019
Same author

Tumor Chemo-Radiotherapy with Rod-Shaped and Spherical Gold Nano Probes: Shape and Active Targeting Both Matter.

Theranostics·2019

Related Experiment Video

Updated: Mar 7, 2026

Nuclei Isolation from Adult Mouse Kidney for Single-Nucleus RNA-Sequencing
06:00

Nuclei Isolation from Adult Mouse Kidney for Single-Nucleus RNA-Sequencing

Published on: September 20, 2021

5.4K

Research progress in single‑cell omics technologies for kidney disease (Review).

Jia Xu1, Ziwei Chen2, Shengyao Li3

  • 1Hospital of Chengdu University of Traditional Chinese Medicine, School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, P.R. China.

International Journal of Molecular Medicine
|March 6, 2026
PubMed
Summary

Single-cell omics technologies reveal kidney cell diversity and immune cell dynamics in renal ageing and disease. This approach aids in understanding disease mechanisms and identifying new therapeutic targets for kidney disorders.

Keywords:
biomarkercellular senescenceimmune mechanismkidney diseasessingle‑cell omics technologiestargeted therapy

More Related Videos

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

791
Efficient Vascularization of Kidney Organoids through Intracelomic Transplantation in Chicken Embryos
07:35

Efficient Vascularization of Kidney Organoids through Intracelomic Transplantation in Chicken Embryos

Published on: February 17, 2023

2.4K

Related Experiment Videos

Last Updated: Mar 7, 2026

Nuclei Isolation from Adult Mouse Kidney for Single-Nucleus RNA-Sequencing
06:00

Nuclei Isolation from Adult Mouse Kidney for Single-Nucleus RNA-Sequencing

Published on: September 20, 2021

5.4K
Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

791
Efficient Vascularization of Kidney Organoids through Intracelomic Transplantation in Chicken Embryos
07:35

Efficient Vascularization of Kidney Organoids through Intracelomic Transplantation in Chicken Embryos

Published on: February 17, 2023

2.4K

Area of Science:

  • Nephrology
  • Immunology
  • Genomics

Background:

  • The kidney's complex cellular structure, including diverse specialized cells, poses challenges for studying kidney diseases.
  • Understanding renal cell heterogeneity is crucial for advancing kidney research.

Purpose of the Study:

  • To review the applications of single-cell omics in renal ageing and kidney diseases.
  • To highlight how these technologies elucidate immune cell roles and interactions in the kidney.

Main Methods:

  • Application of single-cell omics technologies.
  • Analysis of renal cell diversity and heterogeneity.
  • Identification and characterization of immune cell populations in the kidney.

Main Results:

  • Single-cell omics have uncovered extensive renal cell diversity and heterogeneity.
  • Precise identification of various immune cell types within the kidney is now possible.
  • Dynamic changes in renal immune cells during disease progression have been elucidated.

Conclusions:

  • Single-cell omics provide powerful tools for dissecting kidney disease pathogenesis.
  • These technologies offer insights into immune cell dynamics and interactions in renal disorders.
  • This research lays the foundation for identifying novel therapeutic targets in kidney diseases.