Related Experiment Video
Updated: Mar 7, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Transcatheter Edge-to-Edge Mitral Valve Repair Device Embolization into the Right Lower Pulmonary Vein
Dennis D Kumi1, Pablo Barzallo1, Kumaran S Senthil1
1Department of Medicine, University of Illinois College of Medicine at Peoria, Peoria, Illinois, USA.
Background:
Excellent efficacy and safety have led to an increase in transcatheter edge-to-edge repair (TEER) procedures. MitraClip embolization into the pulmonary veins has not yet been reported in the literature.
Case Summary:
A 77-year-old man in cardiogenic shock with severe mitral regurgitation underwent a MitraClip procedure. Deployment of a second MitraClip was complicated by knotting of the locking threads. Attempts to release these threads led to embolization of the MitraClip into the right lower pulmonary vein. Transesophageal echocardiography-guided retrieval using a gooseneck snare through a multipurpose catheter led to safe clip removal.
Discussion:
MitraClip embolization is a rare event that complicates up to 0.1% of cases. This is to our knowledge the first case report on embolization into the pulmonary veins. Lock-thread failure as the mechanism for embolization is uncommon. Our retrieval assembly, consisting of a gooseneck snare through a long multipurpose catheter then through the MitraClip steerable catheter, provided adequate reach, torque, and maneuverability for safe retrieval.
Take-Home Messages:
The pulmonary veins are a rare location for MitraClip embolization. Appropriate catheter selection and optimal grasp orientation are key to event-free retrieval.
Related Concept Videos
Mitral Stenosis III: Medical Management
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Mitral Regurgitation III: Medical Management
Cardiac Catheterization II: Right Heart Catheterization

