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Related Concept Videos

Burn Injuries01:22

Burn Injuries

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Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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Phases of Wound Repair01:28

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Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
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Related Experiment Video

Updated: Mar 8, 2026

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
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Risk factors for wound infection after burn plastic surgery.

Li-Zhen Xu1, Ying-Zhuo Huang2, Li-Fang Xu3

  • 1Ya'an People's Hospital, Ya'an, Sichuan, China.

Medicine
|March 6, 2026
PubMed
Summary

Identifying key risk factors for burn plastic surgery wound infections is crucial. Diabetes, prolonged surgery, deep burns, large burn areas, multiple antibiotics, poor wound healing, and malnutrition significantly increase infection risk.

Keywords:
burn plastic surgeryrisk factorswound infection

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Area of Science:

  • Plastic Surgery
  • Infectious Disease Epidemiology
  • Burn Care

Background:

  • Postoperative wound infection is a significant complication in burn plastic surgery.
  • Identifying modifiable and non-modifiable risk factors is essential for effective prevention strategies.

Purpose of the Study:

  • To analyze risk factors for wound infection following burn plastic surgery.
  • To explore targeted intervention measures for reducing infection rates in clinical practice.

Main Methods:

  • A retrospective study of 320 patients undergoing burn plastic surgery.
  • Comparison of infection and non-infection groups using univariate and multivariate logistic regression analyses.
  • Data collection included patient demographics, comorbidities, burn characteristics, surgical details, and postoperative outcomes.

Main Results:

  • The overall infection rate was 26.88%.
  • Independent risk factors identified include diabetes, surgery duration ≥ 200 minutes, third-degree burns, burn area ≥ 40%, use of ≥ 2 antibiotics, residual wound presence, and malnutrition.
  • Odds ratios (OR) ranged from 2.759 to 7.092, all statistically significant (P < .05).

Conclusions:

  • Postoperative wound infection is multifactorial, strongly associated with diabetes, prolonged surgery, burn severity and extent, antibiotic regimen, wound healing status, and nutritional status.
  • Comprehensive perioperative assessment and individualized preventive strategies are recommended.
  • Strengthening interventions targeting high-risk factors can reduce infection risk and improve wound healing outcomes.