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Updated: Mar 8, 2026
A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
Published on: September 16, 2017
The temporal mismatch between MRI-based prognostic classification and the therapeutic window
1The Space Information Research Institute, Zhejiang Key Laboratory of Space Information Sensing and Transmission, Hangzhou Dianzi University, Hangzhou, Zhejiang, China; Zhejiang Institute of Artificial Intelligence, Hangzhou, Zhejiang, China.
Abstract:
The characteristic MRI findings in AESD emerge 3-14 days post-onset according to international consensus definitions, creating a temporal mismatch whereby MRI-based prognostic classification may not be available within the critical 24-48 h therapeutic window for neuroprotective interventions such as edaravone.
Insights
Characteristic MRI findings for Acute Encephalopathy with Seizures and Edema (AESD) appear 3-14 days after onset. This delay hinders timely prognostic classification for critical neuroprotective treatments like edaravone.
Area of Science:
- Neurology
- Radiology
- Neuroimaging
Background:
- Acute Encephalopathy with Seizures and Edema (AESD) is a severe neurological condition.
- Early diagnosis and prognosis are crucial for effective treatment, particularly for neuroprotective agents.
