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The temporal mismatch between MRI-based prognostic classification and the therapeutic window.

Yuanhong Xu1, Fan Mo2

  • 1The Space Information Research Institute, Zhejiang Key Laboratory of Space Information Sensing and Transmission, Hangzhou Dianzi University, Hangzhou, Zhejiang, China; Zhejiang Institute of Artificial Intelligence, Hangzhou, Zhejiang, China.

Journal of the Neurological Sciences
|March 6, 2026
PubMed
Summary

Characteristic MRI findings for Acute Encephalopathy with Seizures and Edema (AESD) appear 3-14 days after onset. This delay hinders timely prognostic classification for critical neuroprotective treatments like edaravone.

Keywords:
AESDEdaravoneMRI timingPrognostic markersTherapeutic window

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