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Updated: Jul 5, 2026

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Delayed forebrain excitatory and inhibitory neurogenesis in STRADA-related megalencephaly via mTOR hyperactivity

Tong Pan1, Grace Lin1, Xuan Li2

  • 1Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA.

Stem Cell Reports
|March 6, 2026
PubMed

Keywords:
PMSE syndromeSTRADAbrain organoidcell fate specificationepilepsyinterneuron developmentmTORmTORC1mammalian target of rapamycinmechanistic target of rapamycin

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