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Optimizing Renal Allograft Dysfunction Management: A Systematic Review and Proposed Algorithm for Interventional
Hany M El Hennawy1, Omar Safar2, Ghaleb A Aboalsamh3
1Surgery Department, Section of Transplantation, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Jeddah, Saudi Arabia; King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
Transplantation Proceedings
|March 6, 2026
Summary
Interventional radiology (IR) offers high success for kidney transplant complications, often serving as a first-line treatment. Surgery remains crucial for complex cases, guiding a new management algorithm to improve graft survival.
Area of Science:
- Nephrology
- Transplant Surgery
- Interventional Radiology
Background:
- Kidney transplantation is optimal for end-stage renal disease but faces graft survival threats from post-transplant complications.
- Interventional radiology (IR) presents a minimally invasive alternative to surgery, yet comparative evidence is limited.
Conclusions:
- IR should be considered first-line for many vascular and urological complications; surgery is indispensable for complex/recurrent cases.
- A novel management algorithm is proposed for adult and pediatric recipients, requiring prospective validation.
- Adoption of this algorithm may reduce graft loss and optimize resource use in renal allograft dysfunction management.
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