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Predictive Value of Standardised Remnant Liver Volume Combined with the ALBI-FIB4 Score for Posthepatectomy Liver
Sirui Yang1, Peipei Ye1, Shua Cui1
1Department of Radiology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Abstract:
ABSTRACT Objective: To evaluate the predictive efficacy of standardised remnant liver volume (SRLV) combined with the albumin-bilirubin- fibrosis-4 (ALBI-FIB4) score for posthepatectomy liver failure (PHLF) in patients with hepatocellular carcinoma (HCC).
Study Design:
A descriptive and analytical study. Place and Duration of the Study: Department of Radiology, the Second Affiliated Hospital of Kunming Medical University, Kunming, China, from February 2022 to February 2024.
Methodology:
Clinical and imaging data of 80 patients with HCC who underwent partial hepatectomy were retrospectively analysed. Subjects were divided into two cohorts: those with non-PHLF (n = 62) and those who developed PHLF (n = 18). Receiver operating characteristic (ROC) curve analysis was employed to compare the predictive performance of SRLV, ALBI score, FIB-4 index, ALBI- FIB4 score, SRLV+ALBI score, SRLV+FIB-4 index, and SRLV+ALBI-FIB4 score for the occurrence of PHLF.
Results:
Among the 80 patients, 18 (22.5%) developed PHLF. The SRLV+ALBI-FIB4 scoring model demonstrated superior diagnostic efficacy, with an area under the ROC curve (AUC) of 0.825, outperforming individual and other combined models, including SRLV (AUC = 0.719), ALBI score (AUC = 0.698), FIB-4 index (AUC = 0.679), ALBI-FIB4 score (AUC = 0.773), SRLV+ALBI score (AUC = 0.801), and SRLV+FIB-4 index (AUC = 0.775).
Conclusion:
The SRLV+ALBI-FIB4 scoring model integrates anatomical and functional liver reserve parameters, offering enhanced predictive accuracy for PHLF compared to traditional single- or combined-index models. This approach provides a valuable tool for preoperative risk assessment and surgical decision optimisation in HCC patients.
Key Words:
Hepatocellular carcinoma, Liver failure, Postoperative complications, Liver function tests, MR volumetry, Posthepatectomy, ALB1-FIB4 score.
