Related Experiment Video
Updated: Mar 9, 2026
05:39
A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
Published on: November 30, 2021
4.2K
Deficiency of interleukin-40 prevents intestinal damage in experimental necrotizing enterocolitis by inhibiting
Yunfei Zhang1,2, Cuilian Ye3, Xin Zhong2
1Department of Pediatrics, Chongqing Health Center for Women and Children, Chongqing, China.
Cell Communication and Signaling : CCS
|March 7, 2026
Abstract
No abstract available in PubMed .
Related Concept Videos
01:12Role Of Notch Signalling In Intestinal Stem Cell Renewal
2.6K
Notch signaling was first discovered in Drosophila melanogaster, where it is involved in cell lineage differentiation. Notch signaling regulates the maintenance and differentiation of intestinal stem cells or ISCs by controlling the expression of atonal homolog 1 or Atoh1. Atoh1 directs cells to differentiate into secretory cells.
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
2.6K
01:23Renewal of Intestinal Stem Cells
3.4K
The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the...
3.4K