Bilateral Hippocampal High-Grade Glioma: An Exceptional Rare Entity

We report a 60-year-old woman who presented with a 1-month history of progressive cognitive decline and was found to have bilateral enhancing lesions involving both hippocampi. Histopathological examination confirmed the diagnosis of high-grade glioma. High-grade gliomas arising specifically within the bilateral hippocampi are exceedingly rare and may mimic encephalitic processes, with only a single case previously reported in the literature. Nevertheless, this entity should be considered in the differential diagnosis of bilateral hippocampal lesions.