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Updated: Mar 10, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
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Spatial controls of homology search

Aurèle Piazza1, Angela Taddei2

  • 1Université de Lyon, ENS de Lyon, Université Claude Bernard, CNRS UMR5239, Laboratoire de Biologie et Modélisation de la Cellule, Lyon, France.

Current Opinion in Genetics & Development
|March 9, 2026
PubMed
Summary

Homologous recombination uses RecA/Rad51 filaments to find DNA templates for double-strand break repair. Recent advances reveal this homology search is orchestrated by 3D chromatin organizers and filament dynamics.

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