Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Biological Effects of Radiation

Biological Effects of Radiation

All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Chemical Repair of Radical Damage to the GC Base Pair by DNA-Bound Bisbenzimidazoles.

The journal of physical chemistry. B·2024

Same author

Response of the modified GAFCHROMIC EBT2 radiochromic film to DC glow discharge plasma.

Scientific reports·2024

Same author

Abscopal Gene Expression in Response to Synchrotron Radiation Indicates a Role for Immunological and DNA Damage Response Genes.

Radiation research·2020

Same author

Monitoring DNA Damage and Repair in Peripheral Blood Mononuclear Cells of Lung Cancer Radiotherapy Patients.

Cancers·2020

Same author

A Functional Immune System Is Required for the Systemic Genotoxic Effects of Localized Irradiation.

International journal of radiation oncology, biology, physics·2018

Same author

Radiation Therapy Modulates DNA Repair Efficiency in Peripheral Blood Mononuclear Cells of Patients With Non-Small Cell Lung Cancer.

International journal of radiation oncology, biology, physics·2018

Same journal

A near-infrared ratiometric fluorescence probe for mitochondrial H<sub>2</sub>O<sub>2</sub> imaging in biosystems and water samples.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026

Same journal

Sensitive detection of prostate cancer antigen 3 (PCA3) in urine based upon CRISPR/Cas12a and gold nanorods (AuNRs).

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026

Same journal

Spectroscopic, photometric, and radiation shielding studies of europium-activated red-emitting magnesium borosilicate glasses.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026

Same journal

Benzothiadiazole-based covalent organic frameworks with red-light emission for visual detection of norfloxacin.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026

Same journal

Photophysical behavior of mono- and bis(2'-hydroxyphenyl)-6-(4'-diphenylaminophenyl)pyrimidines: Interplay of ESIPT, ICT, and vibrational nonradiative decay.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026

Same journal

Lanthanide-based metal-organic gels for flexible X-ray imaging.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 10, 2026

Effective Analysis of Human Exposure Conditions with Body-worn Dosimeters in the 2.4 GHz Band

Effective Analysis of Human Exposure Conditions with Body-worn Dosimeters in the 2.4 GHz Band

Published on: May 2, 2018

FBX dosimeter - a theoretical approach for interpretation and optimisation.

Omar M Kotb¹, Pavel N Lobachevsky²

¹Physics Department, Faculty of Science, Zagazig University, 44519, Zagazig, Egypt; Joint Institute for Nuclear Research, Laboratory of radiation biology, Moscow region, Dubna, 141980, Russian Federation.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy

|March 9, 2026

Summary

This summary is machine-generated.

This study introduces a theoretical model for the ferrous sulphate (FBX) chemical dosimeter, explaining the formation of xylenol orange (XO) and Fe3+ complexes. It provides guidelines for optimizing radiation measurements using this dosimeter.

Keywords:

Chemical dosimetry Dose response FBX system Spectrophotometric titration Theoretical approach X-rays

More Related Videos

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Published on: February 20, 2021

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Related Experiment Videos

Last Updated: Mar 10, 2026

Effective Analysis of Human Exposure Conditions with Body-worn Dosimeters in the 2.4 GHz Band

Effective Analysis of Human Exposure Conditions with Body-worn Dosimeters in the 2.4 GHz Band

Published on: May 2, 2018

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Published on: February 20, 2021

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

Chemical dosimetry
Radiation chemistry
Spectrophotometry

Background:

Ferrous sulphate (FBX) chemical dosimetry utilizes xylenol orange (XO) and Fe3+ complex formation for radiation detection.
Previous studies show discrepancies in FBX dosimeter results, necessitating a refined theoretical interpretation.

Purpose of the Study:

To develop a theoretical approach for interpreting FBX dosimeter behavior.
To elucidate the complex formation between XO and Fe3+ ions.
To provide guidelines for optimizing FBX dosimeter measurements.

Main Methods:

Theoretical modeling of binding equilibrium between XO, Fe3+ ions, and their complexes (1:1 and 2:1 stoichiometry).
Spectrophotometric titration of XO with Fe3+ ions.
X-ray irradiation of FBX solutions followed by spectral analysis.

Main Results:

Deconvolution of spectra identified individual XO/Fe3+ complexes (XOFe3+ and XO2Fe3+).
Calculated peak molar extinction coefficients for the complexes at specific wavelengths.
Determined dose response of Fe3+ ion and complex concentrations, indicating generally non-linear calibration curves.
Identified conditions and methods for achieving linear calibration curves at specific wavelengths.

Conclusions:

The theoretical model accurately describes FBX dosimeter behavior based on complex formation.
Understanding complex stoichiometry and binding equilibria is crucial for accurate dosimetry.
The study offers a method to optimize wavelength selection for linear calibration, enhancing FBX dosimeter reliability.