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The phase III MECCA study on metronomic chemo-endocrine therapy in advanced breast cancer-the results that so many
1Department of Oncology, Jagiellonian University-Medical College Hospital, Krakow, Poland.
Chinese Clinical Oncology
|March 9, 2026
Abstract
No abstract available in PubMed .
Keywords:
Breast cancer (BC)cyclin-dependent kinase 4/6 inhibitors (CDK4/6i)estrogen receptor-positive/human epidermal growth factor receptor 2-negative (ER+/HER2−)metronomic chemo-endocrine therapy (metronomic CET)More Related Videos
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Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
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Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...