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Related Concept Videos

Pulse01:05

Pulse

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The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
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Pulse01:16

Pulse

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When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

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In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
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Related Experiment Video

Updated: Mar 10, 2026

Particle Image Velocimetry Investigation of Hemodynamics via Aortic Phantom
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Pulsatility index: Insights into post-stroke haemodynamics.

Christina Shen-Zhuang Yde1, Vladimir V Matchkov1

  • 1Department of Biomedicine, Health, Aarhus University, Denmark.

Neuroscience Insights
|March 9, 2026
PubMed
Summary
This summary is machine-generated.

Acute ischemic stroke patients often have poor outcomes despite successful treatment. This review highlights how assessing blood flow pulsatility could improve diagnosis and prognosis for stroke recovery.

Keywords:
MRIneuroanatomyneuroimagingneuropathologystroke

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Area of Science:

  • Neurology
  • Cardiovascular Research
  • Biomedical Engineering

Background:

  • Acute ischemic stroke is a major cause of global disability.
  • Recanalization therapies improve outcomes but functional independence remains a challenge for many.
  • Cerebral hemodynamic alterations post-stroke are complex and not fully understood.

Purpose of the Study:

  • To review current knowledge on pulsatile hemodynamics in stroke occlusion-reperfusion.
  • To emphasize the clinical potential of pulsatility assessment as a diagnostic and prognostic biomarker.

Main Methods:

  • Literature review of animal and clinical studies on cerebral hemodynamics in stroke.
  • Analysis of existing data on pulsatile flow patterns during occlusion-reperfusion.
  • Synthesis of findings to highlight the role of pulsatility.

Main Results:

  • Pulsatile hemodynamics play a complex role in stroke pathophysiology.
  • Alterations in pulsatility are observed in occlusion-reperfusion scenarios.
  • Pulsatility assessment shows promise as a clinical tool.

Conclusions:

  • Understanding pulsatile hemodynamics is crucial for stroke recovery.
  • Pulsatility assessment may offer valuable prognostic and diagnostic insights.
  • Further research into pulsatility biomarkers could enhance clinical management of stroke patients.