Related Experiment Video
Updated: Mar 10, 2026

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah
Published on: June 24, 2025
What leads to vaccine compliance? Evidence from healthcare workers
Alessandro Demichelis1, Marco Marini1,2, Dario Menicagli1
1IMT Scuola Alti Studi Lucca, Lucca, Italy.
Background:
Vaccine hesitancy is a problematic phenomenon for vaccination campaigns. It played a significant role during the recent COVID-19 pandemic, where the role of HealthCare Workers (HCW) was particularly relevant. Understanding the motivation of HCW regarding vaccines is, therefore, paramount.
Design And Methods:
We presented an online questionnaire to 5283 Italian HCW to investigate the role played by personal reasons and the potential perception of risk, the social environment, and the vaccine efficacy and safety perception in affecting HCW willingness to adhere to the vaccination campaign.
Results:
First, we discovered that those who took the vaccine to minimize health risk tended to vaccinate earlier, whereas those who did it due to social pressure received it later. Second, that those who indicated acquaintances as more important than the workplace in their vaccination choice showed more altruistic-related reasons to vaccinate, and the reverse held true. Third, that regarding two salient features of the vaccine, namely safety and efficacy, only the former was playing a role in the willingness to vaccinate, whereas the latter did not show an impact.
Conclusions:
The lessons that can be taken from these results are that future communication campaigns that push toward a timely vaccination should focus less on the social pressure, especially the one related to work environments, and more on the internal motivations of workers. Moreover, we can conclude that emphasizing the safety features of vaccines tend to play a more significant role in shaping vaccine behaviors than emphasizing efficacy.
More Related Videos
Related Concept Videos
Obedience
Vaccinations
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
PPE Use in Healthcare Settings II: Doffing
Nurses' Legal Responsibilities III
Cultivating a culture of collaboration and mutual respect among nurses transcends mere enhancement...
Nurses' Legal Responsibilities II
Communication between nurses and...

