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Extracompartmental Two-Injection Technique for Treating De Quervain Tenosynovitis
Tyler S Iodence1, William F McCormick2, Jeffrey A Marchessault2
1Orthopedic Surgery, Watauga Orthopaedics, Bristol, USA.
Cureus
|March 9, 2026
Summary
A novel two-injection technique for De Quervain tenosynovitis (DQT) significantly improved pain and grip strength. This extracompartmental approach offers a promising alternative to traditional injections for DQT treatment.
Area of Science:
- Orthopedics
- Hand Surgery
- Musculoskeletal Disorders
Background:
- De Quervain tenosynovitis (DQT) is a common condition affecting the tendons of the thumb.
- Traditional treatments, including intracompartmental steroid injections, carry risks and potential complications.
Purpose of the Study:
- To evaluate the efficacy of a novel extracompartmental two-injection technique for treating De Quervain tenosynovitis.
- To compare the outcomes of this new technique with baseline measurements and reported results of other injection methods.
Main Methods:
- A prospective study involving fifteen patients diagnosed with DQT.
- Patients underwent a novel extracompartmental two-injection technique.
- Pain (Visual Analog Scale), grip strength, and physical examination findings were assessed before and four weeks after treatment.
Main Results:
- 100% of patients showed symptom improvement and absent physical exam findings.
- 73% of patients achieved complete symptom resolution.
- 93% of patients experienced improved grip strength post-treatment.
- The technique demonstrated significant improvement in pain and grip strength compared to baseline.
Conclusions:
- The extracompartmental two-injection technique is effective for De Quervain tenosynovitis.
- This method offers comparable short-term outcomes to other techniques while potentially reducing pain and risks.
- The reproducible technique provides a valuable option for clinicians and patients managing DQT.

