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Updated: Mar 10, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
Small-vessel Disease in a Patient with Atrial Flutter: Unveiling a Potential Vascular Mechanism of
Sebastian Weyand1, Karin Klingel2, Peter Seizer1
1Medizinische Klinik II-Kardiologie und Angiologie, Ostalb-Klinikum Aalen, Aalen, Germany.
Abstract:
A 65-year-old man presented with new-onset exertional dyspnea. The predominant abnormality was a marked concentric thickening of the arteriolar walls with strong smooth muscle actin positivity, consistent with small-vessel disease (SVD). This case illustrates a potential mechanism of tachycardia-induced cardiomyopathy (TIC), in which SVD may contribute to impaired myocardial perfusion and reversible left ventricular dysfunction under persistent tachycardia.
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