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Updated: Aug 1, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Comparable outcomes following combined ACL and ALL reconstruction using a 1-strand versus 2-strand back-and-forth
Guillaume Andre1, Damien Block1, Olivier Gosselin1
1COUBORTHO, Centre Coubertin/Hôpital-clinique Claude Bernard, ELSAN Metz France.
Hamstring graft techniques for combined anterior cruciate ligament (ACL) and anterolateral ligament (ALL) reconstruction showed no significant differences in post-operative laxity or clinical outcomes. Both 1-strand and 2-strand methods effectively restore knee stability and function.
Area of Science:
- Orthopedic surgery
- Sports medicine
- Biomechanical engineering
Background:
- Combined anterior cruciate ligament (ACL) and anterolateral ligament (ALL) injuries often require surgical reconstruction.
- Hamstring grafts are commonly used for ACL reconstruction, but optimal techniques for combined ACL and ALL reconstruction are still debated.
- Understanding the biomechanical and clinical differences between graft techniques is crucial for improving patient outcomes.
Purpose of the Study:
- To compare post-operative laxity and clinical outcomes of combined ACL and ALL reconstruction using hamstring grafts with a 1-strand versus a 2-strand back-and-forth technique.
- To evaluate the effectiveness of each technique in restoring knee stability and function.
Main Methods:
- Retrospective assessment of 348 patients (2-strand) and 130 patients (1-strand) undergoing combined ACL and ALL reconstruction.
- Propensity score matching created comparable cohorts (70 patients each).
- Pre- and post-operative assessments included KOOS-12, Lysholm, Tegner, ACL-RSI scores, physical exams (jerk test, Lachman grade), and arthrometer measurements (anterior translation, internal rotation).
Main Results:
- After propensity score matching and accounting for follow-up losses and revisions, 58 patients (2-strand) and 59 patients (1-strand) were analyzed.
- No significant differences were found between the 1-strand and 2-strand groups in post-operative differential laxity (anterior translation, internal rotation).
- Clinical outcome scores (KOOS-12, ACL-RSI, Lysholm, Tegner) and retear rates were comparable between the two techniques.
Conclusions:
- The 1-strand and 2-strand back-and-forth hamstring graft techniques for combined ACL and ALL reconstruction yield similar post-operative laxity.
- Both techniques demonstrate comparable functional and clinical outcomes, including return to sport and activity levels.
- These findings suggest that both 1-strand and 2-strand techniques are equally effective for restoring knee stability and function in combined ACL and ALL reconstructions.
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