Related Experiment Video
Updated: May 7, 2026

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
Published on: November 7, 2020
Epidemiological characteristics and risk factors for severity of product-related injuries in children during
Jie Chen1, Yanqi Lan1, Zhuoping Zhang2
1Xiamen Center for Disease Control and Prevention, Xiamen, Fujian, China.
Insights
The COVID-19 pandemic
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- The COVID-19 pandemic created a natural experiment to study the impact of non-pharmaceutical interventions (NPIs) on childhood injuries.
- Understanding how NPIs affect injury patterns and severity is crucial for public health strategies during emergencies.
Purpose of the Study:
- To assess the impact of NPIs on the epidemiological characteristics of product-related injuries in children.
- To determine the factors influencing the severity of these injuries during different pandemic phases.
Main Methods:
- Analysis of 39,245 product-related injury cases in children (1-17 years) from 2016-2024 using the Xiamen Injury Surveillance System.
- Categorization of the study period into pre-pandemic, during NPIs, and post-NPIs phases.
- Multivariable logistic regression models with interaction terms to analyze injury severity and effect modification by NPIs.
Main Results:
- During NPIs, home injuries increased to 56.38%, with rises in foreign body injuries and burns/scalds.
- NPIs significantly increased severe injury risk for products like agro-forestry-fishery items, household appliances, and toys.
- Conversely, injury severity at schools/public places decreased in the post-NPIs period compared to pre-pandemic.
Conclusions:
- Non-pharmaceutical interventions altered childhood injury risks, particularly increasing the severity of injuries from home-related products.
- Targeted product safety interventions within homes are essential during public health emergencies.
Introduction:
This study utilized the "natural experiment" created by the COVID-19 pandemic to assess the impact of non-pharmaceutical interventions (NPIs) on the epidemiological characteristics and determinants of the severity of product-related injuries among children.
Methods:
We analyzed data on product-related injuries in children aged 1 to 17 years from the Xiamen Injury Surveillance System between 2016 and 2024. The study period was categorized into three phases: pre-pandemic, during NPIs, and post-NPIs. Multivariable logistic regression models were constructed, adjusting for demographic and injury-related confounders. Interaction terms (period × injury location, period × product category) were included to analyze the independent effect of the NPIs period on the risk of severe injury (requiring hospital admission) and its effect modification.
Results:
A total of 39,245 cases were included. During the NPIs period, the proportion of injuries occurring at home peaked at 56.38%, with notable increases in the proportions of foreign body injuries and burns/scalds. In the post-NPIs period, the proportion of injuries occurring at schools and public places rebounded to 18.07%. While the NPIs period was not independently associated with injury severity in the main effects model, interaction analysis revealed that, compared to furniture-related injuries in the pre-pandemic period, the risk of severe injury was significantly higher during the NPIs period for injuries involving agro-forestry-fishery products (aOR = 15.59, 95% CI: 4.70-51.75), household appliances (aOR = 4.20, 95% CI: 1.37-12.88), and children's toys (aOR = 3.47, 95% CI: 1.29-9.33). Conversely, the severity risk of injuries occurring at schools and public places in the post-NPIs period was significantly lower than in the pre-pandemic period (aOR = 0.47, 95% CI: 0.23-0.99).
Conclusion:
NPIs reshaped the risk landscape of childhood injuries, significantly increasing the severity of injuries associated with specific home-related products (e.g., toys and household appliances). These findings underscore the necessity of integrating targeted product safety interventions within the home environment during public health emergency responses.
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Pharmacokinetics: Drug–Food and Drug–Viral Interactions
Pharmaceutical Poisoning: Potential Scenarios
Investigation of Disease Outbreaks

