Methodological review: Prioritizing a future research agenda for overcoming immunization implementation barriers in...

Area of Science:

• Health Systems Research
• Implementation Science
• Public Health Policy

Background:

• Research prioritization is crucial for addressing health system challenges, particularly in resource-limited settings.
• This study focuses on a priority-setting workshop methodology to guide future immunization research in Pakistan.

Purpose of the Study:

• To analyze the methodology of a priority-setting workshop designed to identify research needs for overcoming immunization implementation barriers in Pakistan.
• To evaluate the integration of Dot Voting, Impact Feasibility Matrix, and Delphi-informed thematic categorization in a participatory research prioritization process.

Main Methods:

• A methodological review of an immunization priority-setting workshop conducted in June 2024.
• The workshop involved 26 subject matter experts and utilized Dot Voting and Impact Feasibility Matrix, followed by a Delphi-informed thematic categorization.
• Analysis of the workshop design and implementation to assess its effectiveness in identifying research priorities.

Main Results:

• The Dot Voting method identified technical and contextual research questions related to immunization implementation.
• The Impact Feasibility Matrix confirmed priorities and highlighted underemphasized areas like cost-effectiveness.
• A Delphi-informed process synthesized 23 prioritized questions into four key themes: data systems, digital health, workforce capacity, and equitable access.

Conclusions:

• Structured and participatory processes are valuable for identifying priority research areas in immunization.
• The success of such processes depends on reflectivity, inclusivity, and managing complex challenges.
• Future efforts should balance real-world limitations with strategies for equity and stakeholder engagement in low- and middle-income countries.