Developing a Complex Intervention Plan for Physical Activity in Overweight and Obese Endometrial Cancer Patients: A...

Area of Science:

• Oncology
• Exercise Science
• Public Health

Background:

• Obesity is a significant risk factor for endometrial cancer (EC) and impacts treatment outcomes.
• Existing research on physical activity (PA) for EC patients lacks tailored, evidence-based guidance.
• PA interventions are crucial for managing weight and improving survival in EC patients.

Purpose of the Study:

• To develop a comprehensive physical activity (PA) intervention program specifically for overweight and obese endometrial cancer (EC) patients.
• To integrate theoretical frameworks, empirical evidence, expert opinions, and stakeholder perspectives for standardized PA guideline implementation.
• To create a resource that assists clinical providers in managing EC patients with obesity.

Main Methods:

• The study utilized the Evidence-Based Nursing Practice Pathway and the Medical Research Council's Framework for Complex Interventions.
• A three-phase development process included preparatory work, intervention design and implementation, and refinement via Delphi consultation.
• Methods involved evidence searches, semistructured interviews, and expert consultations to inform program content and materials.

Main Results:

• A PA program framework was developed, covering preinstruction, implementation, and maintenance strategies.
• Instructional materials, including posters, brochures, videos, and checklists, were created for clinical integration.
• The program integrates evidence and stakeholder feedback for practical application in clinical settings.

Conclusions:

• This is the first tailored PA program developed for overweight and obese endometrial cancer patients.
• The intervention's rigorous design, based on complex intervention frameworks and expert input, can enhance clinical practice.
• The program has the potential to improve tumor remission rates and fertility outcomes in EC patients.