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Conducting Respiratory Oscillometry in an Outpatient Setting
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Use of Impulse Oscillometry in Patients with Chronic Obstructive Pulmonary Disease
Burcu Öztürk Şahin1, Nurdan Köktürk2
1Department of Pulmonary Diseases, University of Health Sciences Türkiye, Gülhane Faculty of Medicine, Ankara, Türkiye.
Thoracic Research and Practice
|March 9, 2026
Summary
Impulse oscillometry system (IOS) shows increased airway resistance in chronic obstructive pulmonary disease (COPD) patients, correlating with standard pulmonary function tests. This non-invasive method aids in assessing COPD pathology and small airway function.
Area of Science:
- Pulmonary Medicine
- Respiratory Physiology
Background:
- Spirometry is standard for obstructive lung diseases but has low quality and utilization.
- Impulse oscillometry system (IOS) is non-invasive, requires minimal cooperation, and is suitable for pediatrics.
- IOS may clarify small airway disease in chronic obstructive pulmonary disease (COPD) mechanisms.
Purpose of the Study:
- Compare IOS parameters in COPD patients versus healthy individuals.
- Determine the relationship between IOS parameters and standard pulmonary function tests (PFTs).
- Hypothesize that IOS-detected airway resistance is higher in COPD patients.
Main Methods:
- 104 subjects (62 COPD, 42 healthy) underwent spirometry, DLCO, lung volumes, and IOS.
- Comparative analysis of IOS parameters between COPD and control groups.
- Correlation analysis between IOS parameters and PFTs.
Main Results:
- COPD patients had significantly lower FEV1, FVC, FEV1/FVC, FEF 25-75, and DLCOadj.
- COPD patients exhibited significantly higher RV and TLC.
- IOS parameters R5%, Z5%, Fres, R5-R20/R5%, and AX were significantly higher in COPD patients.
- Moderate negative correlation found between FEF 25-75% and R5-R20.
- Weak positive correlation found between RV/TLC ratio and R5-R20.
Conclusions:
- Airway resistance is increased in COPD patients, as indicated by IOS.
- IOS parameters correlate with small airway function measures in standard PFTs.
- IOS is a valuable, non-invasive tool complementing PFTs for comprehensive COPD assessment.
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