Successful dissolution of a giant bezoar after enzyme complex therapy

Bezoars are an uncommon cause of intestinal obstruction and may be managed using several approaches. Because recurrence can occur, invasive or surgical treatments should not be considered first-time when conservative options are feasible. We report the case of a 67-year-old man with a previously asymptomatic giant gastric phytobezoar who developed subocclusive symptoms. A review of the literature was performed to evaluate available treatment strategies, as no standard therapy exists to date for giant bezoars. A conservative approach was selected using an oral enzyme complex (Digeston Plus®) containing digestive enzymes and probiotic bacteria. The patient completed a three-month treatment course, leading to symptom resolution and near-complete dissolution of the bezoar without the need of invasive intervention.