Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

PhotIQA: A photoacoustic image data set with image quality ratings.

Scientific data·2026

Same author

The confounding effects of skin colour in photoacoustic imaging.

Nature communications·2026

Same author

Efficacy of Credelio Quattro™ chewable tablets containing lotilaner, moxidectin, pyrantel, and praziquantel against Ctenocephalides felis and Rhipicephalus sanguineus infestations on dogs.

Parasites & vectors·2026

Same author

SPEND-hSRS imaging of fumarate uncovers mitochondrial metabolic heterogeneity.

bioRxiv : the preprint server for biology·2026

Same author

Efficacy of a novel chewable tablet (Credelio Quattro™) containing lotilaner, moxidectin, praziquantel, and pyrantel for the prevention of heartworm disease (Dirofilaria immitis) in dogs.

Parasites & vectors·2026

Same author

Physician Attitudes Embedded Within Electronic Medical Records of Persons With and Without Serious Mental Illness.

Schizophrenia bulletin·2026

Same journal

Learning Moisture-Induced Damage From Vision: Diffusion Models for Real-Time Monitoring of Additive Manufacturing Processes.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same journal

Intrinsic Dual-Phase Regulated GeSe<sub>2</sub> Nanoparticles Triggered by Ball-Milling Treatment for Photonic Multi-Valued Logic Circuits.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same journal

A Plant Photoregulator-Inspired S-Type Heterojunction System for Diabetic Keratopathy via Tri-Modal Light-Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same journal

eEF1G Orchestrates Translation to Ensure Meiotic Progression in Transcriptionally Quiescent Spermatocytes.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same journal

Ultrasound-Recharged Sub-Nanometer Palladium Catalysts for on-Demand and Self-Terminating Bioorthogonal Prodrug Activation in Cancer Therapy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same journal

Graphene Aerogels With Spherical Pore Structure for Broad Frequency Regulation and Enhanced Low-Frequency Response.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 24, 2026

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Published on: October 16, 2017

Early Radiation Therapy Response Assessment Using Multi-Scale Photoacoustic Imaging.

Thierry L Lefebvre^1,2, Mariam-Eleni Oraiopoulou^1,2, Ellie V Bunce^1,2

¹Department of Physics, University of Cambridge, Cambridge, UK.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

|March 9, 2026

Summary

This summary is machine-generated.

Photoacoustic imaging (PAI) identifies biomarkers predicting radiation therapy (RT) response in breast cancer models. PAI reveals tumor oxygenation and vascular changes, aiding in monitoring treatment effectiveness and guiding radioresistance assessment.

Keywords:

breast cancer medical image analysis photoacoustic imaging radiation oncology radiation therapy treatment response

More Related Videos

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry

Published on: January 17, 2020

Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

Published on: July 15, 2020

Related Experiment Videos

Last Updated: Jun 24, 2026

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Published on: October 16, 2017

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry

Ovarian Cancer Detection Using Photoacoustic Flow Cytometry

Published on: January 17, 2020

Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

Published on: July 15, 2020

Area of Science:

Biomedical Imaging
Cancer Research
Radiotherapy

Background:

Clinical need for biomarkers predicting radiation therapy (RT) response.
Tumor oxygenation and vasculature are critical factors in RT efficacy.
Current methods lack in vivo assessment of tumor vascular response to RT.

Purpose of the Study:

To identify biomarkers of RT response using multi-scale photoacoustic imaging (PAI).
To compare RT response in two human breast cancer xenograft models (MCF7 and MDA-MB-231).
To investigate regimen-specific vascular effects of hypofractionated versus ablative RT.

Main Methods:

Multi-scale and multispectral tomographic photoacoustic imaging (PAI) in vivo.
PAI performed at pre-RT, post-RT, and endpoint, supported by ex vivo immunohistochemistry.
Comparison of hypofractionated and ablative RT schemes in MCF7 and MDA-MB-231 xenografts.

Main Results:

MCF7 xenografts, with denser vasculature, showed better RT response than MDA-MB-231.
Higher pre-RT oxygenation correlated with improved outcomes.
PAI detected regimen-specific vascular changes, including vessel pruning and altered oxygenation.

Conclusions:

PAI can identify surrogate biomarkers for predicting RT response.
PAI effectively monitors tumor vascular response to different RT schemes.
PAI demonstrates potential for assessing radioresistance and guiding treatment decisions.