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Updated: Mar 11, 2026

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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
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Fairness aware subset selection for advancing equity in skin cancer detection
Yehuda Perry1, Abdulaziz A Almuzaini2, Adewole S Adamson3
1Department of Library and Information Science, Rutgers University, New Brunswick, NJ 08901, United States.
Summary
FAIR-SCAN, a new data-centric framework, improves artificial intelligence (AI) for skin cancer detection by strategically selecting training data. This approach enhances accuracy and fairness across all skin tones, addressing bias in AI diagnostics.
Area of Science:
- Artificial Intelligence in Medicine
- Dermatology
- Medical Diagnostics
Background:
- Skin cancer is a prevalent malignancy, with AI showing promise for early detection.
- Current AI models exhibit performance disparities, particularly underperforming on darker skin tones (Fitzpatrick Types V and VI).
- Existing fairness methods primarily focus on algorithmic adjustments, often overlooking crucial data quality and representation issues.
Purpose of the Study:
- To introduce FAIR-SCAN (Fairness and Accuracy through Ranking-Based Subset Selection for Skin Cancer Detection), a novel data-centric framework.
- To enhance fairness and accuracy in AI-driven skin cancer detection models.
- To address performance disparities across different skin tones in AI diagnostic tools.
Main Methods:
- FAIR-SCAN employs a data-centric framework utilizing subset selection guided by marginal contribution score (MCS) estimation.
- Data points are ranked based on their contribution to both model accuracy and fairness.
- An optimal subset of data is selected for training AI models, evaluated on Diverse Dermatology Images (DDI) and Fitzpatrick 17K datasets.
Main Results:
- FAIR-SCAN demonstrated improved balance in accuracy, True Positive Rate, and False Positive Rate across various skin tones.
- The method achieved this improvement while reducing the training dataset size by 50%.
- FAIR-SCAN outperformed existing algorithm-focused fairness methods in enhancing equity.
Conclusions:
- Strategic data selection is paramount for mitigating bias in AI-driven diagnostics.
- FAIR-SCAN's data-centric approach significantly enhances both the precision and equity of skin cancer detection.
- This framework supports the development of trustworthy and clinically deployable AI systems for skin cancer diagnosis.

