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Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
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Pharmacogenomics: Identification of New Drug Targets01:29

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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
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Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...
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Related Experiment Video

Updated: Mar 11, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
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Implementing Genomic Medicine in a Federally Qualified Health Center: Assessing Readiness through a Mixed-Methods

Emory William Heffernan1, Paramita Das2, Larry Hearld3

  • 1Department of Neurology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Public Health Genomics
|March 9, 2026
PubMed
Summary
This summary is machine-generated.

Genomic medicine implementation in resource-limited Federally Qualified Health Centers (FQHCs) faces barriers like staffing and finances. Strategies include patient engagement and clear leadership for equitable precision medicine adoption.

Keywords:
CFIR frameworkFederally Qualified Health CentersGenomic medicineHealth equityImplementation scienceMixed methods

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Area of Science:

  • Genomic medicine
  • Precision medicine
  • Implementation science

Background:

  • Genomic medicine offers personalized care but lacks implementation evidence in resource-constrained settings.
  • Federally Qualified Health Centers (FQHCs) serve vulnerable populations, making them crucial for equitable genomic medicine access.

Purpose of the Study:

  • To evaluate the readiness of an Alabama FQHC to integrate genomic medicine into routine care.
  • To identify barriers and facilitators for genomic medicine implementation in an FQHC setting.

Main Methods:

  • A mixed-methods approach was used, including surveys, interviews, concept mapping, and nominal group technique.
  • The CFIR-ERIC Implementation Strategy Matching Tool was utilized to prioritize strategies.

Main Results:

  • Key barriers identified were staffing shortages, financial constraints, and language obstacles.
  • Facilitators included strong commitment to quality care, mission alignment, and supportive leadership.
  • High-priority implementation strategies included patient/family involvement, tailored education, and designated leadership.

Conclusions:

  • FQHCs can implement genomic services by focusing on culturally sensitive patient engagement.
  • Structured provider training and defined leadership roles are essential for successful genomic medicine adoption.