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Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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Related Experiment Video

Updated: May 7, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Published on: September 11, 2013

Acute Retinal Necrosis Presenting with Exudative Retinal Detachment: Clinical Features and Outcomes.

Arjun Watane¹, Shabtab Nasir^2,3, Soumyava Basu²

¹Yale Eye Center, Department of Ophthalmology, Yale University, New Haven, CT, USA.

Ocular Immunology and Inflammation

|March 9, 2026

Summary

Exudative retinal detachment (ERD) is a rare but significant finding in Acute Retinal Necrosis (ARN), indicating severe inflammation. While ERD resolved in all patients, half developed rhegmatogenous retinal detachment.

Keywords:

Acute retinal necrosis exudative retinal detachment intravenous methyl prednisolone occlusive vasculitis

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Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

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Last Updated: May 7, 2026

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Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

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Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

Area of Science:

Ophthalmology
Retinal Diseases
Infectious Diseases

Background:

Acute Retinal Necrosis (ARN) is a severe viral retinitis.
Exudative retinal detachment (ERD) is an uncommon complication of ARN.

Purpose of the Study:

To analyze the clinical characteristics and outcomes of patients with ARN presenting with ERD.
To understand the implications of ERD in ARN patients.

Main Methods:

Retrospective observational study of ARN cases with ERD.
Data collected from tertiary eye care centers in India (2015-2024).
Reviewed clinical records of 322 ARN cases, focusing on 21 eyes with ERD.

Main Results:

ERD occurred in 4.34% of ARN cases (21 eyes/14 patients).
ARN with ERD showed extensive involvement (90% four quadrants) and high rates of occlusive vasculitis (90%).
ERD resolved in all patients within ~11 days, but 50% developed subsequent rhegmatogenous retinal detachment (RRD).

Conclusions:

ERD in ARN signifies extensive disease activity and severe inflammation.
Eyes with ERD exhibit higher rates of occlusive vasculitis and more severe retinal involvement.
ERD is a critical indicator of aggressive ARN, often preceding RRD.