Life After Death: Ethical Considerations of CPR in Brain-Dead Pediatric Organ Donors

Jenny Kingsley1,2, Miriam Piven Cotler3,4, Brenda Barnum2,5

  • 1University of Southern California Keck School of Medicine, Los Angeles, California.

Pediatrics
|March 9, 2026
PubMed

Insights

Organ-preserving cardiopulmonary resuscitation (OP-CPR) for pediatric organ donation presents ethical challenges. Perspectives vary on its justification, balancing organ availability with donor dignity and communication needs.

Area of Science:

  • Medical Ethics
  • Pediatric Critical Care
  • Organ Donation and Transplantation

Background:

  • Organ-preserving cardiopulmonary resuscitation (OP-CPR) is used in pediatric organ donation after neurological determination of death.
  • Ethical tensions exist between maximizing organ viability and respecting the deceased donor's bodily integrity.

Purpose of the Study:

  • To explore the ethical complexities of OP-CPR in pediatric organ donation.
  • To present diverse perspectives on the justification and implementation of OP-CPR.

Main Methods:

  • Case study analysis of a pediatric patient (JJ).
  • Presentation of three distinct viewpoints: an organ procurement organization ethicist, pediatric critical care physicians/bioethicists, and pediatric intensive care unit nurses.

Main Results:

  • An OPO ethicist supports OP-CPR for justice and organ availability.
  • Physicians/bioethicists question OP-CPR's ethical justification due to low success rates and potential harm to donor dignity.
  • Nurses report communication challenges, moral distress, and policy issues with OP-CPR.

Conclusions:

  • Clear guidelines and improved collaboration between PICU teams and OPOs are necessary for OP-CPR.
  • Ethical frameworks must address conscientious objection and commitment in OP-CPR practices.
  • Further dialogue is needed to navigate the ethical landscape of pediatric organ donation.

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