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Published on: March 29, 2018
Epidemiological trends in enamel hypomineralisation and molar-incisor hypomineralisation: a systematic review and
Nour Ammar1,2, Karl-Ferdinand Fresen1, Falk Schwendicke1
1Department of Conservative Dentistry, Periodontology and Digital Dentistry, University Hospital, Ludwig-Maximilians Universität München, Munich, Germany.
Objective:
Recently, the systematic review and meta-analysis "Epidemiological Trends in Enamel Hypomineralisation and Molar-Incisor Hypomineralisation: A Systematic Review and Meta-Analysis" was published in Clinical Oral Investigations. In 2025 a reader brought the omission of an epidemiological study from North America to the attention of the author group.
Materials And Methods:
After checking the eligibility for inclusion we aimed at updating the meta-analysis. After inclusion of this overlooked study the systematic review and meta-analysis covers 139 studies and data from a total of 199,999 participants.
Results:
For North America, the MIH prevalence estimate decreased slightly from 0.239 (95% CI: 0.144-0.334) to 0.223 (95% CI: 0.140-0.306). Notably, the global prevalence estimate for MIH remained unchanged at 0.155 (95% CI: 0.144-0.166).
Conclusion:
The addition of the overlooked study influenced slightly the MIH outcome for North America but had no impact on the previously drawn conclusions.
Clinical Relevance:
Enamel hypomineralisation/ Molar incisor hypomineralisation is prevalent across the globe and needs attention by dental practitioners.
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