ASSOCIATION PROPERTIES OF COMPLETE BLOOD COUNT FOR LEVELS OF THYROID STIMULATING HORMONE

Thyroid disorders, hypothyroidism or hyperthyroidism, are frequently encountered in medical practice. Estimating the significance of MPV as an indicator of thrombotic propensity in hypothyroidism would be helpful and looking for association of complete blood count with thyroid-stimulating hormone is quite useful in discovering and monitoring thyroid disorders.

To find any correlations between complete blood count parameters and thyroid-stimulating hormone levels and exploring complete blood count (CBC) as a marker of cardiovascular risk and inflammation. Looking for cutoff values in CBC indices to help indicate thyroid-stimulating hormone levels in suspected patients.

In a retrospective study, 92 patients were randomly chosen from patients suspected of hypothyroidism, and complete blood count and thyroid stimulating hormone tests were performed, followed by statistical analysis.

Positive significant correlation existed between mean platelet volume (MPV) and thyroid stimulating hormone (TSH). Significant difference in Mean TSH in patients with MPV equal to 10 fL and more and patients with MPV more less than 10 fL. Significant difference in Mean TSH in patients with platelets distribution width (PDW) equal to 12 and less and patients with PDW more than 12. Positive significant correlation between MPV and PDW was found. A significant difference in means of MPV between subjects of less than 0.4 mU/L TSH and subjects of TSH more than 4 mU/L, and between subjects of TSH between 0.4- 4.0 mU/L and subjects of TSH level more than 4.0 mU/L.

MPV and PDW have a correlation with TSH levels represented by a cutoff values of 12 and 10 fL for PDW and MPV respectively are associated hypothyroidism state. Other CBC parameters have no significant association value for TSH level.