Pelvic Exenteration: Oncological and Surgical Outcomes From a Single Tertiary Statewide Service

Area of Science:

• Surgical Oncology
• Gastrointestinal Surgery
• Pelvic Malignancies

Background:

• Multidisciplinary management has improved outcomes for advanced pelvic malignancies.
• Pelvic exenteration involves en bloc resection to achieve negative margins (R0).
• Royal Brisbane and Women's Hospital (RBWH) is a statewide referral center for pelvic exenteration since 2012.

Purpose of the Study:

• To present oncological and surgical outcomes of pelvic exenteration at RBWH.
• Evaluate the safety and efficacy of pelvic exenteration in a statewide referral center.
• Compare outcomes with national and collaborative data.

Main Methods:

• Retrospective cohort study.
• Data collected from medical records of patients undergoing pelvic exenteration at RBWH (2012-2023).
• Ethics approval obtained from Metro North HREC.

Main Results:

• 139 patients underwent pelvic exenteration (117 total, 22 partial).
• R0 resection rate was 90.4%.
• 1, 2, and 5-year overall survival rates were 89.9%, 82.0%, and 62.9% respectively; disease-specific survival rates were 92.7%, 83.8%, and 66.8%.

Conclusions:

• Pelvic exenteration surgery can be safely performed in lower-volume centers.
• Outcomes are comparable to national and higher-volume center data.
• Demonstrates equivalent oncological and surgical results.