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Updated: Mar 11, 2026

09:21
Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
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Embryonal Rhabdomyosarcoma of the Diaphragm in a Two-Year-Old Boy
Shuhei Sato1, Takuya Kamio1, Katsuyuki Tanaka1
1Pediatrics, The Jikei University School of Medicine, Tokyo, JPN.
Cureus
|March 10, 2026
Summary
Pediatric diaphragmatic rhabdomyosarcoma, though rare, can present with ascites. This embryonal type, classified as high-risk, showed significant response to chemotherapy, leading to omission of surgery and no recurrence after 16 months.
Area of Science:
- Pediatric Oncology
- Skeletal Muscle Tumors
- Diaphragmatic Neoplasms
Background:
- Primary diaphragmatic tumors are rare in children.
- Rhabdomyosarcoma is the most common malignant diaphragmatic tumor in pediatric patients.
- Embryonal rhabdomyosarcoma arises from primitive mesenchymal cells.
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