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Summary of Best Evidence for the Management and Recurrence Prevention of Febrile Seizures in Children
Rongzhu Tang1, Min Wang2, Xue He1
1Department of Pediatrics, Suining Central Hospital, Suining, Sichuan, People's Republic of China.
Insights
This study synthesizes evidence on preventing and managing febrile seizures in children. It provides guidance for healthcare professionals to improve clinical nursing practices and patient care.
Area of Science:
- Pediatrics
- Evidence-Based Practice
- Clinical Nursing
Background:
- Febrile seizures are common in children.
- Standardized guidelines for their prevention and management are crucial.
- Evidence-based practice enhances clinical decision-making.
Purpose of the Study:
- To systematically review and synthesize the best available evidence on febrile seizure prevention and management in children.
- To develop evidence-based guidance for healthcare professionals.
- To inform clinical nursing practice and improve patient outcomes.
Main Methods:
- Comprehensive literature search across multiple databases (e.g., PubMed, Cochrane Library, Embase) up to July 2025.
- Independent quality evaluation and data extraction by two researchers.
- Synthesis of evidence from clinical decisions, guidelines, expert consensus, best practices, and systematic reviews.
Main Results:
- Inclusion of 20 literature sources.
- Development of 29 best evidence statements.
- Key themes include clinical assessment, diagnosis, hospitalization indications, risk assessment, treatment (pharmacological and non-pharmacological), and caregiver support.
Conclusions:
- This study provides a comprehensive summary of best evidence for febrile seizure management.
- Healthcare professionals should use clinical judgment to apply evidence based on patient circumstances and preferences.
- The findings support evidence-based clinical nursing practice for febrile seizures in children.
Objective:
This study aims to systematically search, screen, evaluate, and summarize the best evidence related to the prevention and management of febrile seizures in children, with the goal of providing evidence-based guidance for clinical practice in this field.
Methods:
A comprehensive search was conducted across multiple databases, including UpToDate, Joanna Briggs Institute (JBI), Guidelines International Network, Agency for Healthcare Research and Quality, Scottish Intercollegiate Guidelines Network, National Institute for Health and Care Excellence, Registered Nurses Association of Ontario, the Cochrane Library, Embase, PubMed, Web of Science, China National Knowledge Internet (CNKI), SinoMed, and WanFang database. The search deadline was from database establishment to July, 2025. Two researchers independently evaluated the quality of the included literature and extracted and summarized the evidence.
Results:
Twenty literature sources were included, comprising 3 clinical decision, 7 guidelines, 4 expert consensus, 1 best practice, and 5 systematic reviews. Through integration of these sources, 29 best evidence statements were ultimately developed, covering 6 major themes: Clinical assessment and diagnosis, Indications of hospitalization, risk assessment, non-pharmacological treatment, pharmacological treatment, as well as caregiver support and follow-up.
Conclusion:
This study summarizes the best evidence for the prevention and management of febrile seizures in children. In clinical application, healthcare professionals should make professional judgment and select evidence based on clinical circumstances and the preferences of the child, thereby providing a more scientifically grounded basis for clinical nursing practice.
Trial And Protocol Registration:
This study was based on the evidence summary reporting specifications of the Fudan University Center for the Evidence-based Nursing, the register name is "Evidence summary for prevention and management of febrile seizures in children", the registration number is "ES20246803".
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