[Imaging Analysis and Dementia Screening]

This review clarifies the concept of dementia screening and examines its current status and challenges. Screening differs from diagnostic assessment in that it serves as an entry point for early detection and preventive intervention. Current screening indicators include cognitive tests, imaging analyses (MRI and PET), blood biomarkers, and genetic factors. However, no single robust marker has been established for the preclinical stage, making the integration of multiple modestly discriminative indicators essential. Looking ahead, the development of low-cost screening models-leveraging Japan's brain dock datasets and advances in blood testing technologies-represents a promising direction for the field.