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Dementia

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
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Updated: Mar 11, 2026

Using Retinal Imaging to Study Dementia

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

[Imaging Analysis and Dementia Screening].

¹Department of Radiology, Johns Hopkins University School of Medicine.

Brain and Nerve = Shinkei Kenkyu No Shinpo

|March 10, 2026

Summary

This summary is machine-generated.

Dementia screening aims for early detection and intervention, utilizing various indicators like cognitive tests and biomarkers. Integrating multiple markers is key due to the lack of a single robust preclinical indicator.

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Last Updated: Mar 11, 2026

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Published on: August 7, 2017

Area of Science:

Neurology
Gerontology
Public Health

Background:

Dementia screening is crucial for early detection and preventive interventions.
Distinguishing screening from diagnostic assessment is vital for appropriate patient pathways.

Purpose of the Study:

To clarify the concept of dementia screening.
To examine the current status and challenges of dementia screening methods.

Main Methods:

Review of current dementia screening indicators.
Analysis of cognitive tests, neuroimaging (MRI, PET), blood biomarkers, and genetic factors.
Assessment of challenges in preclinical dementia detection.

Main Results:

No single robust biomarker exists for the preclinical stage of dementia.
Integration of multiple, modestly discriminative indicators is essential for effective screening.
Current screening methods face challenges in identifying preclinical dementia.

Conclusions:

Future dementia screening models should be low-cost.
Leveraging large datasets (e.g., Japan's brain dock) and advanced blood tests can improve screening.
Developing integrated, multi-modal screening approaches is a promising direction.